Executive Order on the Safe, Secure, and Trustworthy Development and Use of Artificial Intelligence
United States (Federal) | E.O. 14110
Categories
Key Requirements
Directed HHS to develop an AI assurance policy for healthcare, establish an AI safety program for clinical error reporting, develop a strategy for regulating AI in drug development, and ensure AI use by federally-funded providers complies with nondiscrimination laws. Tasked NIST with AI risk management framework standards.
Regulated Parties
All federal agencies; indirectly AI developers and healthcare providers receiving federal funds via HHS, FDA, ONC directives
Enforcement
White House AI Council coordinated implementation across federal agencies; HHS Secretary responsible for healthcare-specific directives
Sources
Notes
Most comprehensive U.S. AI governance action to date. Over 100 federal agency actions were completed before rescission. HHS released its Strategic Plan for AI in Health on January 10, 2025, ten days before rescission.
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