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FDORA — Predetermined Change Control Plans for AI/ML Medical Devices

United States (Federal) | H.R. 2617 (Pub. L. 117-328), Div. FF, Title III, Section 3308

Year Enacted
2022
Date Signed
Dec 29, 2022
Effective Date
Dec 29, 2022
Status
Enacted
Enacted as part of the Consolidated Appropriations Act, 2023; added Section 515C to the FD&C Act

Categories

Provider Clinical Use Other

Key Requirements

Adds Section 515C to the FD&C Act authorizing FDA to approve predetermined change control plans (PCCPs) for medical devices. Manufacturers with an approved PCCP can update AI-enabled device software without submitting a new application for each modification, as long as changes are consistent with the pre-approved plan.

Regulated Parties

AI/ML medical device manufacturers seeking 510(k) clearance, De Novo authorization, or PMA approval

Enforcement

FDA (Center for Devices and Radiological Health)

Sources

Notes

Critical statutory authority for adaptive AI/ML medical devices. FDA issued final PCCP guidance on December 3, 2024, specifically for AI-enabled device software functions.

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